Structural Refinement by Direct Mapping Reveals Assembly Inconsistencies near Hi-C Junctions

High-throughput chromosome conformation capture (Hi-C) is widely used for scaffolding in de novo assembly because it produces highly contiguous genomes, but its indirect statistical approach can introduce connection errors. We employed optical mapping (Bionano Genomics) as an orthogonal scaffolding...

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Detalles Bibliográficos
Autores principales: Marcolungo, Luca, Vincenzi, Leonardo, Ballottari, Matteo, Cecchin, Michela, Cosentino, Emanuela, Mignani, Thomas, Limongi, Antonina, Ferraris, Irene, Orlandi, Matteo, Rossato, Marzia, Delledonne, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861903/
https://www.ncbi.nlm.nih.gov/pubmed/36679033
http://dx.doi.org/10.3390/plants12020320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861903/
https://www.ncbi.nlm.nih.gov/pubmed/36679033
http://dx.doi.org/10.3390/plants12020320

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