ATP13A2 Gene Silencing in Drosophila Affects Autophagic Degradation of A53T Mutant α-Synuclein

Mutations in ATP13A2 (PARK9), an autophagy-related protein, cause Kufor–Rakeb syndrome, an autosomal recessive, juvenile-onset form of parkinsonism. α-Synuclein (α-syn) is a presynaptic neuronal protein that forms toxic aggregates in Parkinson’s disease (PD). We studied α-syn aggregation and autopha...

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Detalles Bibliográficos
Autores principales: Dhanushkodi, Nisha R., Abul Khair, Salema B., Ardah, Mustafa T., Haque, M. Emdadul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861907/
https://www.ncbi.nlm.nih.gov/pubmed/36675288
http://dx.doi.org/10.3390/ijms24021775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861907/
https://www.ncbi.nlm.nih.gov/pubmed/36675288
http://dx.doi.org/10.3390/ijms24021775

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