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An Adenovirus-Based Recombinant Herpes Simplex Virus 2 (HSV-2) Therapeutic Vaccine Is Highly Protective against Acute and Recurrent HSV-2 Disease in a Guinea Pig Model

Genital herpes (GH) has become one of the most common sexually transmitted diseases worldwide, and it is spreading rapidly in developing countries. Approximately 90% of GH cases are caused by HSV-2. Therapeutic HSV-2 vaccines are intended for people already infected with HSV-2 with the goal of reduc...

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Detalles Bibliográficos
Autores principales: Wan, Mingming, Yang, Xiao, Sun, Jie, Ding, Xue, Chen, Zhijun, Su, Weiheng, Cai, Linjun, Hou, Ali, Sun, Bo, Gao, Feng, Jiang, Chunlai, Zhou, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861952/
https://www.ncbi.nlm.nih.gov/pubmed/36680259
http://dx.doi.org/10.3390/v15010219