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Carbohydrate-Small Molecule Hybrids as Lead Compounds Targeting IL-6 Signaling

In the past 25 years, a number of efforts have been made toward the development of small molecule interleukin-6 (IL-6) signaling inhibitors, but none have been approved to date. Monosaccharides are a diverse class of bioactive compounds, but thus far have been unexplored as a scaffold for small mole...

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Detalles Bibliográficos
Autores principales: Schultz, Daniel C., Pan, Li, Wang, Tiffany, Booker, Conner, Hyder, Iram, Hanold, Laura, Rubin, Garret, Ding, Yousong, Lin, Jiayuh, Li, Chenglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861960/
https://www.ncbi.nlm.nih.gov/pubmed/36677735
http://dx.doi.org/10.3390/molecules28020677