Cargando…
Carbohydrate-Small Molecule Hybrids as Lead Compounds Targeting IL-6 Signaling
In the past 25 years, a number of efforts have been made toward the development of small molecule interleukin-6 (IL-6) signaling inhibitors, but none have been approved to date. Monosaccharides are a diverse class of bioactive compounds, but thus far have been unexplored as a scaffold for small mole...
Autores principales: | Schultz, Daniel C., Pan, Li, Wang, Tiffany, Booker, Conner, Hyder, Iram, Hanold, Laura, Rubin, Garret, Ding, Yousong, Lin, Jiayuh, Li, Chenglong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9861960/ https://www.ncbi.nlm.nih.gov/pubmed/36677735 http://dx.doi.org/10.3390/molecules28020677 |
Ejemplares similares
-
The Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Induces Apoptosis in Medulloblastoma and Glioblastoma Cells
por: Ball, Sarah, et al.
Publicado: (2011) -
A novel small molecule LLL12B inhibits STAT3 signaling and sensitizes ovarian cancer cell to paclitaxel and cisplatin
por: Zhang, Ruijie, et al.
Publicado: (2021) -
LLL12B, a Novel Small-Molecule STAT3 Inhibitor, Induces Apoptosis and Suppresses Cell Migration and Tumor Growth in Triple-Negative Breast Cancer Cells
por: Pan, Li, et al.
Publicado: (2022) -
Anti-Angiogenic Activity of a Small Molecule STAT3 Inhibitor LLL12
por: Bid, Hemant K., et al.
Publicado: (2012) -
Biocatalytic synthesis of peptidic natural products and related analogues
por: Liu, Dake, et al.
Publicado: (2021)