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Reduction in Lens Epithelial Cell Senescence Burden through Dasatinib Plus Quercetin or Rapamycin Alleviates D-Galactose-Induced Cataract Progression

Senescent cells accumulate in aged organisms and promote the progression of age-related diseases including cataracts. Therefore, we aimed to study the therapeutic effects of senescence-targeting drugs on cataracts. In this study, a 28-day D-galactose-induced cataract rat model was used. The opacity...

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Detalles Bibliográficos
Autores principales: Wang, Yinhao, Tseng, Yulin, Chen, Keyu, Wang, Xinglin, Mao, Zebin, Li, Xuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862066/
https://www.ncbi.nlm.nih.gov/pubmed/36662053
http://dx.doi.org/10.3390/jfb14010006