A Structure-Based View on ABC-Transporter Linked to Multidrug Resistance

The discovery of the first ATP-binding cassette (ABC) transporter, whose overexpression in cancer cells is responsible for exporting anticancer drugs out of tumor cells, initiated enormous efforts to overcome tumor cell multidrug resistance (MDR) by inhibition of ABC-transporter. Because of its many...

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Detalles Bibliográficos
Autores principales: Huang, Jiahui, Ecker, Gerhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862083/
https://www.ncbi.nlm.nih.gov/pubmed/36677553
http://dx.doi.org/10.3390/molecules28020495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862083/
https://www.ncbi.nlm.nih.gov/pubmed/36677553
http://dx.doi.org/10.3390/molecules28020495

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