Cargando…
A Structure-Based View on ABC-Transporter Linked to Multidrug Resistance
The discovery of the first ATP-binding cassette (ABC) transporter, whose overexpression in cancer cells is responsible for exporting anticancer drugs out of tumor cells, initiated enormous efforts to overcome tumor cell multidrug resistance (MDR) by inhibition of ABC-transporter. Because of its many...
Autores principales: | Huang, Jiahui, Ecker, Gerhard F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862083/ https://www.ncbi.nlm.nih.gov/pubmed/36677553 http://dx.doi.org/10.3390/molecules28020495 |
Ejemplares similares
-
ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal
por: Choi, Cheol-Hee
Publicado: (2005) -
ABC transporters and the hallmarks of cancer: roles in cancer aggressiveness beyond multidrug resistance
por: Muriithi, Wanjiru, et al.
Publicado: (2020) -
Overcoming Multidrug Resistance: Flavonoid and Terpenoid Nitrogen-Containing Derivatives as ABC Transporter Modulators
por: M. F. Gonçalves, Bruno, et al.
Publicado: (2020) -
Schistosome ABC multidrug transporters: From pharmacology to physiology
por: Greenberg, Robert M.
Publicado: (2014) -
Predicting drug resistance related to ABC transporters using unsupervised Consensus Self-Organizing Maps
por: Estrada-Tejedor, Roger, et al.
Publicado: (2018)