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Structural Modifications of siRNA Improve Its Performance In Vivo

The use of small interfering RNA (siRNA) in the clinic gives a wide range of possibilities for the treatment of previously incurable diseases. However, the main limitation for biomedical applications is their delivery to target cells and organs. Currently, delivery of siRNA to liver cells is a solve...

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Detalles Bibliográficos
Autores principales: Chernikov, Ivan V., Ponomareva, Ulyana A., Chernolovskaya, Elena L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862127/
https://www.ncbi.nlm.nih.gov/pubmed/36674473
http://dx.doi.org/10.3390/ijms24020956