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Differential Regulation of Glucosylceramide Synthesis and Efflux by Golgi and Plasma Membrane Bound ABCC10

Glucosylceramide (GlcCer) synthesis by the enzyme glucosylceramide synthase (GCS) occurs on the cytosolic leaflet of the Golgi and is the first important step for the synthesis of complex glycosphingolipids (GSLs) that takes place inside the lumen. Apart from serving as a precursor for glycosylation...

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Detalles Bibliográficos
Autores principales: Iqbal, Jahangir, Otaibi, Abeer Al, Mubarak, Sindiyan Alshaikh, Alqarni, Ali, Bakillah, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862172/
https://www.ncbi.nlm.nih.gov/pubmed/36678216
http://dx.doi.org/10.3390/nu15020346