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ATP and nucleic acids competitively modulate LLPS of the SARS-CoV2 nucleocapsid protein
SARS-CoV-2 nucleocapsid (N) protein with very low mutation rates is the only structural protein which not only functions to package viral genomic RNA, but also manipulates host-cell machineries, thus representing a key target for drug development. Recent discovery of its liquid-liquid phase separati...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862227/ https://www.ncbi.nlm.nih.gov/pubmed/36681763 http://dx.doi.org/10.1038/s42003-023-04480-3 |