Optimization of the Process for Preparing Bivalent Polysaccharide Conjugates to Develop Multivalent Conjugate Vaccines against Streptococcus pneumoniae or Neisseria meningitidis and Comparison with the Corresponding Licensed Vaccines in Animal Models

OBJECTIVE: This study aimed to describe, optimize and evaluate a method for preparing multivalent conjugate vaccines by simultaneous conjugation of two different bacterial capsular polysaccharides (CPs) with tetanus toxoid (TT) as bivalent conjugates. METHODS: Different molecular weights (MWs) of po...

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Detalles Bibliográficos
Autores principales: Huang, Fang, Jing, Xiao-bing, Li, Yin-bo, Wang, Qian, Liu, Si-li, Yang, Zhi-rong, Feng, Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Huazhong University of Science and Technology 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862236/
https://www.ncbi.nlm.nih.gov/pubmed/36680685
http://dx.doi.org/10.1007/s11596-022-2652-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862236/
https://www.ncbi.nlm.nih.gov/pubmed/36680685
http://dx.doi.org/10.1007/s11596-022-2652-y

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