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Mass cytometry analysis identifies T cell immune signature of aplastic anemia and predicts the response to cyclosporine

Aplastic anemia (AA) is an auto-activated T cell–mediated bone marrow failure. Cyclosporine is often used to treat non-severe AA, which demonstrates a more heterogeneous condition than severe AA. The response rate to cyclosporine is only around 50% in non-severe AA. To better predict response to cyc...

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Detalles Bibliográficos
Autores principales: Zhang, Lele, Mao, Jin, Lian, Yu, Liang, Qian, Li, Weiwang, Zhao, Jingyu, Pan, Hong, Gao, Zhen, Fang, Liwei, Yuan, Weiping, Chu, Yajing, Shi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862246/
https://www.ncbi.nlm.nih.gov/pubmed/36680600
http://dx.doi.org/10.1007/s00277-023-05097-6