The Role of Myeloperoxidase in Clozapine-Induced Inflammation: A Mechanistic Update for Idiosyncratic Drug-Induced Agranulocytosis

The risk of idiosyncratic drug-induced agranulocytosis (IDIAG) markedly constrains the use of clozapine, a neuroleptic with unparalleled efficacy. Most clozapine patients experience an early inflammatory response, likely a necessary step in IDIAG onset. However, most patients do not progress to IDIA...

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Detalles Bibliográficos
Autores principales: Sernoskie, Samantha Christine, Jee, Alison, Uetrecht, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862306/
https://www.ncbi.nlm.nih.gov/pubmed/36674761
http://dx.doi.org/10.3390/ijms24021243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862306/
https://www.ncbi.nlm.nih.gov/pubmed/36674761
http://dx.doi.org/10.3390/ijms24021243

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