Antifibrotic Effects of Caffeine, Curcumin and Pirfenidone in Primary Human Keratocytes

We evaluated the small molecules (AFM) caffeine, curcumin and pirfenidone to find non-toxic concentrations reducing the transformation of activated human corneal stromal keratocytes (aCSK) to scar-inducing myofibroblasts (MYO-SF). CSK were isolated from 16 human corneas unsuitable for transplantatio...

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Detalles Bibliográficos
Autores principales: Talpan, Delia, Salla, Sabine, Seidelmann, Nina, Walter, Peter, Fuest, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862324/
https://www.ncbi.nlm.nih.gov/pubmed/36674976
http://dx.doi.org/10.3390/ijms24021461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862324/
https://www.ncbi.nlm.nih.gov/pubmed/36674976
http://dx.doi.org/10.3390/ijms24021461

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