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Autoinflammation in Syndromic Hidradenitis Suppurativa: The Role of AIM2

Background: AIM2 is a key cytoplasmatic pathogen-sensor that detects foreign DNA from viruses and bacteria; it can also recognize damaged or anomalous presence of DNA, promoting inflammasome assembly and activation with the secretion of IL-1β, thus sustaining a chronic inflammatory state, potentiall...

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Detalles Bibliográficos
Autores principales: Moltrasio, Chiara, Cagliani, Rachele, Sironi, Manuela, Clerici, Mario, Pontremoli, Chiara, Maronese, Carlo Alberto, Tricarico, Paola Maura, Crovella, Sergio, Marzano, Angelo Valerio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862365/
https://www.ncbi.nlm.nih.gov/pubmed/36680007
http://dx.doi.org/10.3390/vaccines11010162