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Autoinflammation in Syndromic Hidradenitis Suppurativa: The Role of AIM2
Background: AIM2 is a key cytoplasmatic pathogen-sensor that detects foreign DNA from viruses and bacteria; it can also recognize damaged or anomalous presence of DNA, promoting inflammasome assembly and activation with the secretion of IL-1β, thus sustaining a chronic inflammatory state, potentiall...
Autores principales: | Moltrasio, Chiara, Cagliani, Rachele, Sironi, Manuela, Clerici, Mario, Pontremoli, Chiara, Maronese, Carlo Alberto, Tricarico, Paola Maura, Crovella, Sergio, Marzano, Angelo Valerio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862365/ https://www.ncbi.nlm.nih.gov/pubmed/36680007 http://dx.doi.org/10.3390/vaccines11010162 |
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