SGLT2 Inhibition, Choline Metabolites, and Cardiometabolic Diseases: A Mediation Mendelian Randomization Study

OBJECTIVE: To investigate the causal role of choline metabolites mediating sodium–glucose cotransporter 2 (SGLT2) inhibition in coronary artery disease (CAD) and type 2 diabetes (T2D) using Mendelian randomization (MR). RESEARCH DESIGN AND METHODS: A two-sample two-step MR was used to determine 1) c...

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Detalles Bibliográficos
Autores principales: Xu, Min, Zheng, Jie, Hou, Tianzhichao, Lin, Hong, Wang, Tiange, Wang, Shuangyuan, Lu, Jieli, Zhao, Zhiyun, Li, Mian, Xu, Yu, Ning, Guang, Bi, Yufang, Wang, Weiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2022
Materias:
Cardiovascular and Metabolic Risk
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862376/
https://www.ncbi.nlm.nih.gov/pubmed/36161993
http://dx.doi.org/10.2337/dc22-0323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862376/
https://www.ncbi.nlm.nih.gov/pubmed/36161993
http://dx.doi.org/10.2337/dc22-0323

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