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TonEBP in Myeloid Cells Promotes Obesity-Induced Insulin Resistance and Inflammation Through Adipose Tissue Remodeling

The phenotypic and functional plasticity of adipose tissue macrophages (ATMs) during obesity plays a crucial role in orchestration of adipose and systemic inflammation. Tonicity-responsive enhancer binding protein (TonEBP) (also called NFAT5) is a stress protein that mediates cellular responses to a...

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Detalles Bibliográficos
Autores principales: Lee, Hwan Hee, Jeong, Gyu Won, Ye, Byeong Jin, Yoo, Eun Jin, Son, Keoung Sun, Kim, Dong Ki, Park, Hye-Kyung, Kang, Byoung Heon, Lee-Kwon, Whaseon, Kwon, Hyug Moo, Choi, Soo Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862453/
https://www.ncbi.nlm.nih.gov/pubmed/36170666
http://dx.doi.org/10.2337/db21-1099