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Evaluation of Safety, Tolerability and Pharmacokinetic Characteristics of SA001 and Its Active Metabolite Rebamipide after Single and Multiple Oral Administration

Dry eye disease (DED) is one of the most common eye diseases caused by multiple factors. Rebamipide, which is currently used to treat peptic ulcer disease, was shown to enhance secretory function and modulate inflammation in animal disease models. Considering the pathophysiology of DED, SA001 was de...

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Detalles Bibliográficos
Autores principales: Bae, Sungyeun, Huh, Ki Young, Oh, Jaeseong, Yu, Kyung-Sang, Kim, Anhye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862565/
https://www.ncbi.nlm.nih.gov/pubmed/36678630
http://dx.doi.org/10.3390/ph16010132