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The Bi-Functional Paxilline Enriched in Skin Secretion of Tree Frogs (Hyla japonica) Targets the KCNK18 and BK(Ca) Channels

The skin secretion of tree frogs contains a vast array of bioactive chemicals for repelling predators, but their structural and functional diversity is not fully understood. Paxilline (PAX), a compound synthesized by Penicillium paxilli, has been known as a specific antagonist of large conductance C...

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Detalles Bibliográficos
Autores principales: Yin, Chuanling, Zeng, Fanpeng, Huang, Puyi, Shi, Zhengqi, Yang, Qianyi, Pei, Zhenduo, Wang, Xin, Chai, Longhui, Zhang, Shipei, Yang, Shilong, Dong, Wenqi, Lu, Xiancui, Wang, Yunfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862588/
https://www.ncbi.nlm.nih.gov/pubmed/36668889
http://dx.doi.org/10.3390/toxins15010070