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Anti-Colorectal Cancer Effects of a Novel Camptothecin Derivative PCC0208037 In Vitro and In Vivo

Colorectal cancer is one of the most common malignancies, and the topoisomerase inhibitor irinotecan (CPT-11)-based chemotherapeutic regimen is currently the first-line treatment with impressive therapeutic efficacy. However, irinotecan has several clinically significant side effects, including diar...

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Detalles Bibliográficos
Autores principales: Li, Min, Wang, Linxu, Wei, Yingjie, Wang, Wenyan, Liu, Zongliang, Zuo, Aixia, Liu, Wanhui, Tian, Jingwei, Wang, Hongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862597/
https://www.ncbi.nlm.nih.gov/pubmed/36678550
http://dx.doi.org/10.3390/ph16010053