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Design, Synthesis, Docking Study, and Antiproliferative Evaluation of Novel Schiff Base–Benzimidazole Hybrids with VEGFR-2 Inhibitory Activity

A new series of Schiff–benzimidazole hybrids 3a–o has been designed and synthesized. The structure of the target compounds was proved by different spectroscopic and elemental analysis tools. The target compounds were evaluated for their in vitro cytotoxic activity against 60 cancer cell lines accord...

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Detalles Bibliográficos
Autores principales: Abd El-Lateef, Hany M., Elbastawesy, Mohammed A. I., Abdelghani Ibrahim, Tamer Mohamed, Khalaf, Mai M., Gouda, Mohamed, Wahba, Mariam G. F., Zaki, Islam, Morcoss, Martha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862622/
https://www.ncbi.nlm.nih.gov/pubmed/36677536
http://dx.doi.org/10.3390/molecules28020481