Development of HIV-Resistant CAR T Cells by CRISPR/Cas-Mediated CAR Integration into the CCR5 Locus

Adoptive immunotherapy using chimeric antigen receptor (CAR) T cells has been highly successful in treating B cell malignancies and holds great potential as a curative strategy for HIV infection. Recent advances in the use of anti-HIV broadly neutralizing antibodies (bNAbs) have provided vital infor...

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Detalles Bibliográficos
Autores principales: Rothemejer, Frederik Holm, Lauritsen, Nanna Pi, Juhl, Anna Karina, Schleimann, Mariane Høgsbjerg, König, Saskia, Søgaard, Ole Schmeltz, Bak, Rasmus O., Tolstrup, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862650/
https://www.ncbi.nlm.nih.gov/pubmed/36680242
http://dx.doi.org/10.3390/v15010202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862650/
https://www.ncbi.nlm.nih.gov/pubmed/36680242
http://dx.doi.org/10.3390/v15010202

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