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Identification of NS2B-NS3 Protease Inhibitors for Therapeutic Application in ZIKV Infection: A Pharmacophore-Based High-Throughput Virtual Screening and MD Simulations Approaches

Zika virus (ZIKV) pandemic and its implication in congenital malformations and severe neurological disorders had created serious threats to global health. ZIKV is a mosquito-borne flavivirus which spread rapidly and infect a large number of people in a shorter time-span. Due to the lack of effective...

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Detalles Bibliográficos
Autores principales: Rehman, Hafiz Muzzammel, Sajjad, Muhammad, Ali, Muhammad Akhtar, Gul, Roquyya, Irfan, Muhammad, Naveed, Muhammad, Bhinder, Munir Ahmad, Ghani, Muhammad Usman, Hussain, Nadia, Said, Amira S. A., Al Haddad, Amal H. I., Saleem, Mahjabeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862652/
https://www.ncbi.nlm.nih.gov/pubmed/36679976
http://dx.doi.org/10.3390/vaccines11010131