Design, synthesis, docking, and biochemical characterization of non-nucleoside SARS-CoV-2 RdRp inhibitors

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a worldwide pandemic. The identification of effective antiviral drugs remains an urgent medical need. In this context, here we report 17 new 1,4-benzopyrone derivatives, which have been designed, synthesized, and characteriz...

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Detalles Bibliográficos
Autores principales: Brindani, Nicoletta, Munafò, Federico, Menichetti, Andrea, Donati, Elisa, Nigro, Michela, Ottonello, Giuliana, Armirotti, Andrea, De Vivo, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862713/
https://www.ncbi.nlm.nih.gov/pubmed/36716583
http://dx.doi.org/10.1016/j.bmc.2023.117179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862713/
https://www.ncbi.nlm.nih.gov/pubmed/36716583
http://dx.doi.org/10.1016/j.bmc.2023.117179

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