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Alpha2-Adrenergic Receptors as a Pharmacological Target for Spike-Wave Epilepsy

Spike-wave discharges are the hallmark of idiopathic generalized epilepsy. They are caused by a disorder in the thalamocortical network. Commercially available anti-epileptic drugs have pronounced side effects (i.e., sedation and gastroenterological concerns), which might result from a low selectivi...

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Detalles Bibliográficos
Autores principales: Sitnikova, Evgenia, Rutskova, Elizaveta, Smirnov, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862736/
https://www.ncbi.nlm.nih.gov/pubmed/36674992
http://dx.doi.org/10.3390/ijms24021477