Design, Synthesis, Biological Evaluation, and Molecular Dynamics Studies of Novel Lapatinib Derivatives

Co-expression of the epidermal growth factor receptor (EGFR, also known as ErbB1) and human epidermal growth factor receptor 2 (HER2) has been identified as a diagnostic or prognostic sign in various tumors. Despite the fact that lapatinib (EGFR/HER2 dual inhibitor) has shown to be successful, many...

Descripción completa

Detalles Bibliográficos
Autores principales: Elkamhawy, Ahmed, Son, Seohyun, Lee, Hwa Young, El-Maghrabey, Mahmoud H., Hamd, Mohamed A. El, Alshammari, Saud O., Abdelhameed, Abeer A., Alshammari, Qamar A., Abdeen, Ahmed, Ibrahim, Samah F., Mahdi, Wael A., Alshehri, Sultan, Alnajjar, Radwan, Choi, Won Jun, Al-Karmalawy, Ahmed A., Lee, Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862743/
https://www.ncbi.nlm.nih.gov/pubmed/36678540
http://dx.doi.org/10.3390/ph16010043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862743/
https://www.ncbi.nlm.nih.gov/pubmed/36678540
http://dx.doi.org/10.3390/ph16010043

Ejemplares similares