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Identifying Dopamine D3 Receptor Ligands through Virtual Screening and Exploring the Binding Modes of Hit Compounds

The dopamine D3 receptor (D3R) is an important central nervous system target for treating various neurological diseases. D3R antagonists modulate the improvement of psychostimulant addiction and relapse, while D3R agonists can enhance the response to dopaminergic stimulation and have potential appli...

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Detalles Bibliográficos
Autores principales: Jin, Hongshan, Wu, Chengjun, Su, Rui, Sun, Tiemin, Li, Xingzhou, Guo, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862751/
https://www.ncbi.nlm.nih.gov/pubmed/36677583
http://dx.doi.org/10.3390/molecules28020527