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The epigenetic factor CHD4 contributes to metastasis by regulating the EZH2/β-catenin axis and acts as a therapeutic target in ovarian cancer

BACKGROUND: The overall survival rate of patients with advanced ovarian cancer (OC) has remained static for several decades. Advanced ovarian cancer is known for its poor prognosis due to extensive metastasis. Epigenetic alterations contribute to tumour progression and therefore are of interest for...

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Detalles Bibliográficos
Autores principales: Wang, Jieyu, Zhong, Fangfang, Li, Jun, Yue, Huiran, Li, Wenzhi, Lu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862813/
https://www.ncbi.nlm.nih.gov/pubmed/36681835
http://dx.doi.org/10.1186/s12967-022-03854-1