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The epigenetic factor CHD4 contributes to metastasis by regulating the EZH2/β-catenin axis and acts as a therapeutic target in ovarian cancer
BACKGROUND: The overall survival rate of patients with advanced ovarian cancer (OC) has remained static for several decades. Advanced ovarian cancer is known for its poor prognosis due to extensive metastasis. Epigenetic alterations contribute to tumour progression and therefore are of interest for...
Autores principales: | Wang, Jieyu, Zhong, Fangfang, Li, Jun, Yue, Huiran, Li, Wenzhi, Lu, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9862813/ https://www.ncbi.nlm.nih.gov/pubmed/36681835 http://dx.doi.org/10.1186/s12967-022-03854-1 |
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