Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases

The nuclear receptors—liver X receptors (LXR α and β) are potential therapeutic targets in cardiovascular and neurodegenerative diseases because of their key role in the regulation of lipid homeostasis and inflammatory processes. Specific oxy(phyto)sterols differentially modulate the transcriptional...

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Detalles Bibliográficos
Autores principales: Zhan, Na, Wang, Boyang, Martens, Nikita, Liu, Yankai, Zhao, Shangge, Voortman, Gardi, van Rooij, Jeroen, Leijten, Frank, Vanmierlo, Tim, Kuipers, Folkert, Jonker, Johan W., Bloks, Vincent W., Lütjohann, Dieter, Palumbo, Marcella, Zimetti, Francesca, Adorni, Maria Pia, Liu, Hongbing, Mulder, Monique T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863018/
https://www.ncbi.nlm.nih.gov/pubmed/36674804
http://dx.doi.org/10.3390/ijms24021290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863018/
https://www.ncbi.nlm.nih.gov/pubmed/36674804
http://dx.doi.org/10.3390/ijms24021290

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