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Concomitant Sub-Chronic Administration of Small-Size Gold Nanoparticles Aggravates Doxorubicin-Induced Liver Oxidative and Inflammatory Damage, Hyperlipidemia, and Hepatic Steatosis

This study examined the effect of gold nanoparticles (AuNPs) on doxorubicin (DOX)-induced liver damage and steatosis in rats and tested its effect mechanism. Wistar male rats were divided into four groups (each of eight rats) as control, AuNPs (50 µL of 10 nm), DOX (15 mg/kg; 3 mg/kg/week), and DOX...

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Detalles Bibliográficos
Autores principales: Alshammari, Ghedeir M., Abdelhalim, Mohamed Anwar, Al-Ayed, Mohammed S., Al-Harbi, Laila Naif, Yahya, Mohammed Abdo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863023/
https://www.ncbi.nlm.nih.gov/pubmed/36677854
http://dx.doi.org/10.3390/molecules28020796