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Engineering enzyme activity using an expanded amino acid alphabet

Enzyme design and engineering strategies are typically constrained by the limited size of nature’s genetic alphabet, comprised of only 20 canonical amino acids. In recent years, site-selective incorporation of non-canonical amino acids (ncAAs) via an expanded genetic code has emerged as a powerful m...

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Detalles Bibliográficos
Autores principales: Birch-Price, Zachary, Taylor, Christopher J, Ortmayer, Mary, Green, Anthony P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863031/
https://www.ncbi.nlm.nih.gov/pubmed/36370045
http://dx.doi.org/10.1093/protein/gzac013