Acute Lung Functional and Airway Remodeling Effects of an Inhaled Highly Selective Phosphodiesterase 4 Inhibitor in Ventilated Preterm Lambs Exposed to Chorioamnionitis

Phosphodiesterase (PDE) inhibition has been identified in animal studies as a new treatment option for neonatal lung injury, and as potentially beneficial for early lung development and function. However, our group could show that the inhaled PDE4 inhibitor GSK256066 could have dose-dependent detrim...

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Detalles Bibliográficos
Autores principales: Hütten, Matthias Christian, Brokken, Tim, Widowski, Helene, Monaco, Tobias, Schneider, Jan Philipp, Fehrholz, Markus, Ophelders, Daan, Kramer, Boris W., Kunzmann, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863035/
https://www.ncbi.nlm.nih.gov/pubmed/36678525
http://dx.doi.org/10.3390/ph16010029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863035/
https://www.ncbi.nlm.nih.gov/pubmed/36678525
http://dx.doi.org/10.3390/ph16010029

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