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Acute Lung Functional and Airway Remodeling Effects of an Inhaled Highly Selective Phosphodiesterase 4 Inhibitor in Ventilated Preterm Lambs Exposed to Chorioamnionitis
Phosphodiesterase (PDE) inhibition has been identified in animal studies as a new treatment option for neonatal lung injury, and as potentially beneficial for early lung development and function. However, our group could show that the inhaled PDE4 inhibitor GSK256066 could have dose-dependent detrim...
Autores principales: | Hütten, Matthias Christian, Brokken, Tim, Widowski, Helene, Monaco, Tobias, Schneider, Jan Philipp, Fehrholz, Markus, Ophelders, Daan, Kramer, Boris W., Kunzmann, Steffen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863035/ https://www.ncbi.nlm.nih.gov/pubmed/36678525 http://dx.doi.org/10.3390/ph16010029 |
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