Calmodulin and Amyloid Beta as Coregulators of Critical Events during the Onset and Progression of Alzheimer’s Disease

Calmodulin (CaM) and a diversity of CaM-binding proteins (CaMBPs) are involved in the onset and progression of Alzheimer’s disease (AD). In the amyloidogenic pathway, AβPP1, BACE1 and PSEN-1 are all calcium-dependent CaMBPs as are the risk factor proteins BIN1 and TREM2. Ca(2+)/CaM-dependent protein...

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Detalles Bibliográficos
Autor principal: O’Day, Danton H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863087/
https://www.ncbi.nlm.nih.gov/pubmed/36674908
http://dx.doi.org/10.3390/ijms24021393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863087/
https://www.ncbi.nlm.nih.gov/pubmed/36674908
http://dx.doi.org/10.3390/ijms24021393

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