Amino Acid Polymorphisms on the Brazilian Strain of Yellow Fever Virus Methyltransferase Are Related to the Host’s Immune Evasion Mediated by Type I Interferon

Since late 2016, a yellow fever virus (YFV) variant carrying a set of nine amino acid variations has circulated in South America. Three of them were mapped on the methyltransferase (MTase) domain of viral NS5 protein. To assess whether these changes affected viral infectivity, we synthesized YFV car...

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Detalles Bibliográficos
Autores principales: Furtado, Nathália Dias, de Mello, Iasmim Silva, de Godoy, Andre Schutzer, Noske, Gabriela Dias, Oliva, Glaucius, Canard, Bruno, Decroly, Etienne, Bonaldo, Myrna C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863089/
https://www.ncbi.nlm.nih.gov/pubmed/36680231
http://dx.doi.org/10.3390/v15010191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863089/
https://www.ncbi.nlm.nih.gov/pubmed/36680231
http://dx.doi.org/10.3390/v15010191

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