Synthesis and DNase I Inhibitory Properties of New Squaramides

Three new monosquaramides (3a–c) were synthesized, characterized by IR, NMR and X-ray, and evaluated for inhibitory activity against deoxyribonuclease I (DNase I) and xanthine oxidase (XO) in vitro. The target compounds inhibited DNase I with IC(50) values below 100 μM, being at the same time more p...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruseva, Nina, Sbirkova-Dimitrova, Hristina, Atanasova, Mariyana, Marković, Ana, Šmelcerović, Žaklina, Šmelcerović, Andrija, Bakalova, Adriana, Cherneva, Emiliya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863136/
https://www.ncbi.nlm.nih.gov/pubmed/36677597
http://dx.doi.org/10.3390/molecules28020538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863136/
https://www.ncbi.nlm.nih.gov/pubmed/36677597
http://dx.doi.org/10.3390/molecules28020538

Ejemplares similares