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Astragaloside IV Targets Macrophages to Alleviate Renal Ischemia-Reperfusion Injury via the Crosstalk between Hif-1α and NF-κB (p65)/Smad7 Pathways

(1) Background: Astragaloside IV (AS-IV) is derived from Astragalus membranous (AM), which is used to treat kidney disease. Macrophages significantly affect the whole process of renal ischemia-reperfusion (I/R). The regulation of macrophage polarization in kidneys by AS-IV was the focus. (2) Methods...

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Detalles Bibliográficos
Autores principales: Tang, Lumin, Zhu, Minyan, Che, Xiajing, Yang, Xiaoqian, Xu, Yao, Ma, Qing, Zhang, Ming, Ni, Zhaohui, Shao, Xinghua, Mou, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863138/
https://www.ncbi.nlm.nih.gov/pubmed/36675720
http://dx.doi.org/10.3390/jpm13010059