CRISPR/Cas9-Mediated Enrichment Coupled to Nanopore Sequencing Provides a Valuable Tool for the Precise Reconstruction of Large Genomic Target Regions

Complete and accurate identification of genetic variants associated with specific phenotypes can be challenging when there is a high level of genomic divergence between individuals in a study and the corresponding reference genome. We have applied the Cas9-mediated enrichment coupled to nanopore seq...

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Detalles Bibliográficos
Autores principales: Lopatriello, Giulia, Maestri, Simone, Alfano, Massimiliano, Papa, Roberto, Di Vittori, Valerio, De Antoni, Luca, Bellucci, Elisa, Pieri, Alice, Bitocchi, Elena, Delledonne, Massimo, Rossato, Marzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863143/
https://www.ncbi.nlm.nih.gov/pubmed/36674592
http://dx.doi.org/10.3390/ijms24021076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863143/
https://www.ncbi.nlm.nih.gov/pubmed/36674592
http://dx.doi.org/10.3390/ijms24021076

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