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CRISPR/Cas9-Mediated Enrichment Coupled to Nanopore Sequencing Provides a Valuable Tool for the Precise Reconstruction of Large Genomic Target Regions
Complete and accurate identification of genetic variants associated with specific phenotypes can be challenging when there is a high level of genomic divergence between individuals in a study and the corresponding reference genome. We have applied the Cas9-mediated enrichment coupled to nanopore seq...
Autores principales: | Lopatriello, Giulia, Maestri, Simone, Alfano, Massimiliano, Papa, Roberto, Di Vittori, Valerio, De Antoni, Luca, Bellucci, Elisa, Pieri, Alice, Bitocchi, Elena, Delledonne, Massimo, Rossato, Marzia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863143/ https://www.ncbi.nlm.nih.gov/pubmed/36674592 http://dx.doi.org/10.3390/ijms24021076 |
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