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Evaluation of Histone Demethylase Inhibitor ML324 and Acyclovir against Cyprinid herpesvirus 3 Infection

Cyprinid herpesvirus 3 (CyHV-3) can cause severe disease in koi and common carp (Cyprinus carpio). Currently, no effective treatment is available against CyHV-3 infection in koi. Both LSD1 and JMJD2 are histone demethylases (HD) and are critical for immediate-early (IE) gene activation essential for...

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Detalles Bibliográficos
Autores principales: Matsuoka, Shelby, Petri, Gloria, Larson, Kristen, Behnke, Alexandra, Wang, Xisheng, Peng, Muhui, Spagnoli, Sean, Lohr, Christiane, Milston-Clements, Ruth, Divilov, Konstantin, Jin, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863241/
https://www.ncbi.nlm.nih.gov/pubmed/36680202
http://dx.doi.org/10.3390/v15010163