Development and Evaluation of (99m)Tc Tricarbonyl Complexes Derived from Flutamide with Affinity for Androgen Receptor

With the objective to develop a potential (99m)Tc radiopharmaceutical for imaging the androgen receptor (AR) in prostate cancer, four ligands bearing the same pharmacophore derived from the AR antagonist flutamide were prepared, labeled with (99m)Tc, and their structures corroborated via comparison...

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Detalles Bibliográficos
Autores principales: Cardoso, María Elena, Decuadra, Paula, Zeni, Maia, Delfino, Agustín, Tejería, Emilia, Coppe, Fátima, Mesa, Juan Manuel, Daher, Grysette, Giglio, Javier, Carrau, Gonzalo, Gamenara, Daniela, Alonso, Omar, Terán, Mariella, Rey, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863320/
https://www.ncbi.nlm.nih.gov/pubmed/36677878
http://dx.doi.org/10.3390/molecules28020820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863320/
https://www.ncbi.nlm.nih.gov/pubmed/36677878
http://dx.doi.org/10.3390/molecules28020820

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