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Metformin Induces Apoptosis in Human Pancreatic Cancer (PC) Cells Accompanied by Changes in the Levels of Histone Acetyltransferases (Particularly, p300/CBP-Associated Factor (PCAF) Protein Levels)

Accumulating evidence (mainly from experimental research) suggests that metformin possesses anticancer properties through the induction of apoptosis and inhibition of the growth and proliferation of cancer cells. However, its effect on the enzymes responsible for histone acetylation status, which pl...

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Detalles Bibliográficos
Autores principales: Szymczak-Pajor, Izabela, Drzewoski, Józef, Świderska, Ewa, Strycharz, Justyna, Gabryanczyk, Anna, Kasznicki, Jacek, Bogdańska, Marta, Śliwińska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863441/
https://www.ncbi.nlm.nih.gov/pubmed/36678613
http://dx.doi.org/10.3390/ph16010115