Mendelian Randomisation Confirms the Role of Y-Chromosome Loss in Alzheimer’s Disease Aetiopathogenesis in Men

Mosaic loss of chromosome Y (mLOY) is a common ageing-related somatic event and has been previously associated with Alzheimer’s disease (AD). However, mLOY estimation from genotype microarray data only reflects the mLOY degree of subjects at the moment of DNA sampling. Therefore, mLOY phenotype asso...

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Detalles Bibliográficos
Autores principales: García-González, Pablo, de Rojas, Itziar, Moreno-Grau, Sonia, Montrreal, Laura, Puerta, Raquel, Alarcón-Martín, Emilio, Quintela, Inés, Orellana, Adela, Andrade, Victor, Adami, Pamela V. Martino, Heilmann-Heimbach, Stefanie, Gomez-Garre, Pilar, Periñán, María Teresa, Alvarez, Ignacio, Diez-Fairen, Monica, Nuñez Llaves, Raul, Olivé Roig, Claudia, Garcia-Ribas, Guillermo, Menéndez-González, Manuel, Martínez, Carmen, Aguilar, Miquel, Buongiorno, Mariateresa, Franco-Macías, Emilio, Saez, Maria Eugenia, Cano, Amanda, Bullido, Maria J., Real, Luis Miguel, Rodríguez-Rodríguez, Eloy, Royo, Jose Luís, Álvarez, Victoria, Pastor, Pau, Piñol-Ripoll, Gerard, Mir, Pablo, Lara, Miguel Calero, Padilla, Miguel Medina, Sánchez-Juan, Pascual, Carracedo, Angel, Valero, Sergi, Hernandez, Isabel, Tàrraga, Lluis, Ramirez, Alfredo, Boada, Mercé, Ruiz, Agustín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863537/
https://www.ncbi.nlm.nih.gov/pubmed/36674414
http://dx.doi.org/10.3390/ijms24020898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863537/
https://www.ncbi.nlm.nih.gov/pubmed/36674414
http://dx.doi.org/10.3390/ijms24020898

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