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Ebola Virus Activates IRE1α-Dependent XBP1u Splicing

Ebola (EBOV) and Marburg virus (MARV) are highly pathogenic filoviruses that influence cellular signaling according to their own needs. MARV has been shown to regulate the IRE1α-dependent unfolded protein response (UPR) to ensure optimal virus replication. It was not known whether EBOV affects this...

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Detalles Bibliográficos
Autores principales: Rohde, Cornelius, Pfeiffer, Sebastian, Baumgart, Sara, Becker, Stephan, Krähling, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863596/
https://www.ncbi.nlm.nih.gov/pubmed/36680162
http://dx.doi.org/10.3390/v15010122