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FISH Diagnostic Assessment of MDM2 Amplification in Liposarcoma: Potential Pitfalls and Troubleshooting Recommendations

MDM2 amplification represents the leading oncogenic pathway and diagnostic hallmark of liposarcoma, whose assessment is based on Fluorescence In Situ Hybridization (FISH) analysis. Despite its diagnostic relevance, no univocal interpretation criteria regarding FISH assessments of MDM2 amplification...

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Detalles Bibliográficos
Autores principales: Gambella, Alessandro, Bertero, Luca, Rondón-Lagos, Milena, Verdun Di Cantogno, Ludovica, Rangel, Nelson, Pitino, Chiara, Ricci, Alessia Andrea, Mangherini, Luca, Castellano, Isabella, Cassoni, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863600/
https://www.ncbi.nlm.nih.gov/pubmed/36674856
http://dx.doi.org/10.3390/ijms24021342