Pharmacokinetic Study of rhIL-18BP and Its Effect on Radiation-Induced Cytokine Changes in Mouse Serum and Intestine

Administration of recombinant human IL-18 binding protein (rhIL-18BP), a natural antagonist of IL-18, significantly increased mouse survival after lethal doses of irradiation. To further understand the roles of IL-18BP in radiation mitigation, we studied the pharmacokinetic (PK) parameters of rhIL-1...

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Detalles Bibliográficos
Autores principales: Cui, Wanchang, Hull, Lisa, Zizzo, Alex, Wang, Li, Lin, Bin, Zhai, Min, Xiao, Mang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863660/
https://www.ncbi.nlm.nih.gov/pubmed/36668761
http://dx.doi.org/10.3390/toxics11010035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863660/
https://www.ncbi.nlm.nih.gov/pubmed/36668761
http://dx.doi.org/10.3390/toxics11010035

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