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CircRNA-PI4KB Induces Hepatic Lipid Deposition in Non-Alcoholic Fatty Liver Disease by Transporting miRNA-122 to Extra-Hepatocytes

Ectopic fat deposition in the liver, known as non-alcoholic fatty liver disease (NAFLD), affects up to 30% of the worldwide population. miRNA-122, the most abundant liver-specific miRNA, protects hepatic steatosis and inhibits cholesterol and fatty acid synthesis in NAFLD. Previously, we have shown...

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Detalles Bibliográficos
Autores principales: Liu, Chang-Hai, Jiang, Wei, Zeng, Qingmin, Wu, Dongbo, Li, Hong, Zhou, Lingyun, Bai, Lang, Tang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863671/
https://www.ncbi.nlm.nih.gov/pubmed/36674813
http://dx.doi.org/10.3390/ijms24021297